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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA5
All Species:
28.18
Human Site:
S460
Identified Species:
62
UniProt:
Q8WWZ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWZ7
NP_061142.2
1642
186508
S460
G
N
V
N
G
N
I
S
F
S
E
I
I
E
P
Chimpanzee
Pan troglodytes
XP_511650
1642
186524
S460
G
N
V
N
G
N
I
S
F
S
E
I
I
E
P
Rhesus Macaque
Macaca mulatta
XP_001082244
1618
183230
S462
D
E
M
D
A
D
P
S
S
H
D
S
F
E
P
Dog
Lupus familis
XP_537573
1642
186609
S460
G
N
V
N
G
N
I
S
F
S
E
I
V
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K448
1642
185876
S460
G
N
I
N
G
N
I
S
L
N
E
I
V
E
P
Rat
Rattus norvegicus
Q8CF82
1642
185792
S460
G
N
I
N
G
N
I
S
L
N
E
I
V
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
S540
G
N
V
N
G
S
I
S
F
S
E
I
I
E
P
Chicken
Gallus gallus
XP_415695
1646
186355
S463
S
S
I
N
G
N
L
S
C
S
E
M
V
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
A463
G
E
V
N
G
T
P
A
I
D
E
S
V
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
D526
N
P
P
N
A
D
S
D
S
L
L
E
G
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
V531
Q
G
E
P
F
D
P
V
F
E
S
I
S
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
42.1
93
N.A.
90
90.2
N.A.
81.3
71.5
N.A.
52
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
100
99.8
62.8
96.7
N.A.
94.8
95.1
N.A.
88
86
N.A.
70.5
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
73.3
73.3
N.A.
93.3
53.3
N.A.
40
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
93.3
93.3
N.A.
100
86.6
N.A.
53.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
28
0
10
0
10
10
0
0
0
0
% D
% Glu:
0
19
10
0
0
0
0
0
0
10
73
10
0
82
10
% E
% Phe:
0
0
0
0
10
0
0
0
46
0
0
0
10
0
0
% F
% Gly:
64
10
0
0
73
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
28
0
0
0
55
0
10
0
0
64
28
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
19
10
10
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
55
0
82
0
55
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
10
10
10
0
0
28
0
0
0
0
0
0
0
73
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
10
10
73
19
46
10
19
10
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
46
0
0
0
0
10
0
0
0
0
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _